个人简介：

  刘梅，女，四川资阳人，农学博士。从事家畜遗传育种方面的科研工作，涉及猪、牛、羊等家畜功能性状遗传标记筛选、重要经济性状遗传基础解析等，以期改良家畜产肉性能。目前，主持1项国家自然基金青年项目，参加1项湖南省农业农村厅项目。已在国际英文期刊发表SCI论文20余篇，其中以第一或通讯作者发表12篇，合计影响因子31.13，单篇最高影响因子6.205。获得国家发明专利6项。参加多次国内外学术会议，并在PAG、全国畜禽遗传标记大会、陕西省遗传学会等多场国内外专业学术会议以及美国农业部Poster Day作学术报告展示并获奖。荣获各种荣誉奖励10余项，包括美国农业部东北区第 29 届科技墙报展览提名奖等。《BMC Genetics》、《BMC Genomics》、《Genomics》杂志审稿人。

教育及科研经历：  

2017.03 – 2019.03, 美国农业部，动物基因组与改良研究实验室，国家公派联合培养博士

2014.09 – 2019.06, 西北农林科技大学，动物遗传育种与繁殖专业，农学博士

2012.09 – 2014.06, 西北农林科技大学，动物遗传育种与繁殖专业，农学硕士

2008.09 – 2012.06, 西北农林科技大学，动物科学专业，农学学士（基地班，“2＋X”本硕博贯通培养） 

研究方向：  

1.       基因组学与表观基因组学分析

2.       产肉性状关键分子调控元件的挖掘及功能机制研究

3.       猪营养与表观遗传调控

项目来源：

1.国家自然科学青年基金，32002166，山羊SNX29基因拷贝数变异对肉质性状的遗传效应及影响机制，2021/01-2023/12，24万元，在研，主持

2.湖南省农业农村厅，省农业农村厅项目，无，现代农业产业技术体系建设，2019-06至2020-06，30万，在研，参加

联系方式： 

Email：Mei.Liu@hunau.edu.cn 

固定电话：18708239532 

地址：第二教学楼505室 

代表性论文： 

1.              Mei Liu, Woodward-Greene J, Kang X, Pan, M. G., Rosen, B., Van Tassell, C. P., ... & Liu, G. E.. Genome-wide CNV analysis revealed variants associated with growth traits in African indigenous goats[J]. Genomics, 2020.(IF=6.205, JCR Q1)

2.              Zihong Kang, Sihuan Zhang, Enhui Jiang, Fachun Wan, Xianyong Lan, Mei Liu*. (2020). Mir-193b regulates the differentiation, proliferation, and apoptosis of bovine adipose cells by targeting the acss2/akt axis. Animals : an Open Access Journal from MDPI, 10(8).( JCR Q1)

3.              Yi Bi, Yuhan Chen, Dongyu Xin, Tingting Liu, Libang He, Yuxin Kang, Chuanying Pan, Weijun Shen, Xianyong Lan, Mei Liu*. (2020). Effect of indel variants within the sorting nexin 29 (snx29) gene on growth traits of goats. Animal Biotechnology(2), 1-6.(ICR Q2)

4.              Mei Liu, Lingzhao Fang, Shuli Liu, Michael G. Pan, Eyal Seroussi, John B. Cole, Li Ma, Hong Chen, and George Liu. Array CGH-based detection of CNV regions and their potential association with reproduction and other economic traits in Holsteins. BMC Genomics 20, no. 1 (2019): 181 (IF= 3.730，JCR Q1)

5.              Mei Liu, Bo Li, Wenwen Peng, Yilei Ma, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Xinglei Qi, George E. Liu, and Hong Chen. LncRNA-MEG3 promotes bovine myoblast differentiation by sponging miR-135. Journal of Cellular Physiology (2019) 234: 18361-18370 (IF = 4.522，JCR Q1)

6.              Mei Liu, Yang Zhou, Benjamin D. Rosen, Curtis P. Van Tassell, Alessandra Stella, Gwenola Tosser-Klopp, Rachel Rupp, Isabelle Palhière, Licia Colli, Brian Sayre, Paola Crepaldi, Lingzhao Fang, Gábor Mészáros, Hong Chen, George E. Liu and the ADAPTmap Consortium. "Diversity of copy number variation in the worldwide goat population." Heredity, 2019, 122(5): 636. (IF = 3.872，JCR Q1)

7.              Shuli Liu, Xiaolong Kang, Claudia R. Catacchio, Mei Liu (co-first author), Lingzhao Fang, Steven G. Schroeder, Wenli Li, Benjamin D. Rosen, Daniela Iamartino, Leopoldo Iannuzzi, Tad S. Sonstegard, Curtis P. Van Tassell, Mario Ventura, Wai Yee Low, John L. Williams, Derek M. Bickhart, and George E. Liu. "Computational detection and experimental validation of segmental duplications and associated copy number variations in water buffalo (Bubalus bubalis). " Functional & Integrative Genomics (2019): 1-11. (IF= 3.889，JCR Q2)

8.              Mei Liu, Bo Li, Tao Shi, Yongzhen Huang, George E. Liu, Xianyong Lan, Chuzhao Lei, and Hong Chen. “Copy number variation of bovine SHH gene is associated with body conformation traits in Chinese beef cattle.” Journal of applied genetics (2019) (IF= 1.725，JCR Q3)

9.              Mei Liu, Chenge Zhang, Xinsheng Lai, Jing Xue, Xianyong Lan, Chuzhao Lei, Yutang Jia, and Hong Chen. "Associations between polymorphisms in the NICD domain of bovine NOTCH1 gene and growth traits in Chinese Qinchuan cattle." Journal of applied genetics 58, no. 2 (2017): 241-247. (IF= 1.655，JCR Q3)

10.       Mei Liu, Bo Li, Yongzhen Huang, Mingjuan Yang, Xianyong Lan, Chuzhao Lei, Weidong Qu, Yueyu Bai, and Hong Chen. "Copy number variation of bovine MAPK10 modulates the transcriptional activity and affects growth traits." Livestock Science 194 (2016): 44-50. (IF= 1.377，JCR Q2)

11.       Mei Liu, Min Liu, Bo Li, Yang Zhou, Yongzhen Huang, Xianyong Lan, Weidong Qu, Xingshan Qi, Yueyu Bai, and Hong Chen. "Polymorphisms of FLII implicate gene expressions and growth traits in Chinese cattle." Molecular and cellular probes 30, no. 4 (2016): 266-272. (IF= 1.403，JCR Q3)

12.       Mei Liu, Mijie Li, Shaoqiang Wang, Yao Xu, Xianyong Lan, Zhuanjian Li, Chuzhao Lei, Dongying Yang, Yutang Jia, and Hong Chen. "Association analysis of bovine Foxa2 gene single sequence variant and haplotype combinations with growth traits in Chinese cattle." Gene 536, no. 2 (2014): 385-392. (IF= 2.138，JCR Q3)

13.       Yue, Binglin, Hui Li, Mei Liu, Jiyao Wu, Mingxun Li, Chuzhao Lei, Bizhi Huang, and Hong Chen. "Characterization of lncRNA–miRNA–mRNA network to reveal potential functional ceRNAs in bovine skeletal muscle." Frontiers in Genetics 10 (2019): 91.

14.       Yang, Liu, Lingyang Xu, Yang Zhou, Mei Liu, Lei Wang, James W. Kijas, Hongping Zhang, Li Li, and George E. Liu. "Diversity of copy number variation in a worldwide population of sheep." Genomics 110, no. 3 (2018): 143-148.

15.       Xu, Yao, Tao Shi, Yang Zhou, Mei Liu, Sebastian Klaus, Xianyong Lan, Chuzhao Lei, and Hong Chen. "A novel PAX7 10-bp indel variant modulates promoter activity, gene expression and contributes to different phenotypes of Chinese cattle." Scientific reports 8, no. 1 (2018): 1724.

16.       Wilson Nandolo, Gábor Mészáros, Liveness Jessica Banda, Timothy N. Gondwe, Doreen Lamuno, Henry Aaron Mulindwa, Helen N. Nakimbugwe, Maria Wurzinger, Yuri T. Utsunomiya, M. Jennifer Woodward-Greene, Mei Liu, George Liu, Curtis P. Van Tassell, Ino Curik, Benjamin D. Rosen and Johann Sölkner. “Timing and extent of inbreeding in African goats”. Frontiers in Genetics, 2019, 10: 537.

17.       Fang Lingzhao, Liu Shuli, Mei Liu... and George E. Liu. Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations[J]. BMC biology, 2019, 17(1): 1-16.

发明专利： 

1. 陈宏、李密杰、刘梅等. 一种检测黄牛PPARGC1A基因单核苷酸多态性的方法(ZL:CN201210124717.8)

2. 陈宏、刘梅、李波等. 一种与秦川牛生长相关的CNV标记的检测方法与应用(ZL:201510867756.0)

3. 陈宏、刘梅、赵晶晶等. 一种检测牛PCAF基因单核苷酸多态性的RFLP方法及试剂盒(ZL201611193789.2)

4. 陈宏、刘梅、李波等. 一种检测MAPK10基因CNV标记的方法与应用（ZL201511030253.4）

5. 陈宏、李波、刘梅等.一种与黄牛生长性状相关的MEG3基因SNP的检测方法及其应用（ZL201611219653.4）

6. 陈宏、刘梅、刘敏等.一种快速检测黄牛FLII基因SNP的RFLP方法及其应用（ZLCN201510866870.1）